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总访问量

2681

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1. Guidelines for the use and interpretation of assays for monitoring.. [24629]
2. Current understanding of osteoarthritis pathogenesis and relevant .. [515]
3. Focal adhesion proteins Pinch1 and Pinch2 regulate bone homeostasi.. [275]
4. Tissue damage negatively regulates LPS-induced macrophage necropto.. [234]
5. Kindlin-2 modulates MafA and β-catenin expression to regulate β-.. [227]
6. Kindlin-2 mediates mechanotransduction in bone by regulating expre.. [197]
7. Lipoatrophy and metabolic disturbance in mice with adipose-specifi.. [184]
8. p204 Is Required for Canonical Lipopolysaccharide-induced TLR4 Sig.. [157]
9. 5-IP7 is a GPCR messenger mediating neural control of synaptotagmi.. [157]
10. Pinch regulates chondrogenesis by control of TGF-beta 1 signaling .. [154]
11. MATRIX REPLENISH IS THE INITIAL REQUIREMENT OF THE OSTEOARTHRITIC .. [143]
12. Kindlin-2 regulates skeletal homeostasis by modulating PTH1R in mi.. [143]
13. Metformin limits osteoarthritis development and progression throug.. [140]
14. Global, regional and national burden of low back pain 1990–2019: .. [140]
15. Mechanical overloading promotes chondrocyte senescence and osteoar.. [136]
16. Osteocytic Kindlin-2 regulates bone mass accrual and maintenance a.. [131]
17. Kindlin-2 Association with Rho GDP-Dissociation Inhibitor alpha Su.. [130]
18. MODERATE FLUID SHEAR STRESS REGULATES EXTRACELLULAR MATRIX HOMEOST.. [129]
19. Kindlin-2 links mechano-environment to proline synthesis and tumor.. [128]
20. TNFR2/14-3-3 signaling complex instructs macrophage plasticity in .. [126]
21. Osteoarthritis: pathogenic signaling pathways and therapeutic targ.. [125]
22. Kindlin-2 preserves integrity of the articular cartilage to protec.. [121]
23. MTORC1 coordinates the autophagy and apoptosis signaling in articu.. [120]
24. Roles of mechanosensitive channel Piezo1/2 proteins in skeleton an.. [119]
25. Kindlin-2 inhibits TNF/NF-κB-Caspase 8 pathway in hepatocytes to .. [118]
26. KINDLIN-2 PRESERVES INTEGRITY OF THE ARTICULAR CARTILAGE TO PROTEC.. [115]
27. PINCH regulates bone homeostasis through its expression in osteocy.. [112]
28. The Rules and Functions of Nucleocytoplasmic Shuttling Proteins [110]
29. Osteoblasts support megakaryopoiesis through production of interle.. [109]
30. Metformin in aging and aging-related diseases: clinical applicatio.. [107]
31. Kindlin Signaling and Bone [106]
32. Metformin attenuates cartilage degeneration in an experimental ost.. [104]
33. Osteocyte β1 integrin loss causes low bone mass and impairs bone .. [104]
34. Kindlin-2 inhibits Nlrp3 inflammasome activation in nucleus pulpos.. [101]
35. Kindlin-2 controls TGF-beta signalling and Sox9 expression to regu.. [100]
36. Mesenchymal stem cells in fibrotic diseases-the two sides of the s.. [100]
37. Kindlin-2 deletion in osteoprogenitors causes severe chondrodyspla.. [99]
38. Pinch loss ameliorates obesity, glucose intolerance and fatty live.. [99]
39. TSC1 regulates osteoclast podosome organization and bone resorptio.. [98]
40. ATF4 Regulates CD4(+) T Cell Immune Responses through Metabolic Re.. [97]
41. ATF4 plays a pivotal role in the development of functional hematop.. [97]
42. Inhibition of Axin1 in osteoblast precursor cells leads to defects.. [96]
43. Moderate fluid shear stress regulates heme oxygenase-1 expression .. [95]
44. Kindlin-2 loss in condylar chondrocytes causes spontaneous osteoar.. [92]
45. Characterization of degenerative human facet joints and facet join.. [91]
46. Kindlin-2 haploinsufficiency protects against fatty liver by targe.. [91]
47. Roles of focal adhesion proteins in skeleton and diseases [91]
48. Kindlin-2 regulates mesenchymal stem cell differentiation through .. [90]
49. mTORC1 Inhibits NF-kappa B/NFATc1 Signaling and Prevents Osteoclas.. [90]
50. Matrix replenishing by BMSCs is beneficial for osteoarthritic temp.. [89]
51. Bone and plasma citrate is reduced in osteoporosis [88]
52. Roles of leader and follower cells in collective cell migration [88]
53. Impaired Bone Homeostasis in Amyotrophic Lateral Sclerosis Mice wi.. [87]
54. Signaling via PINCH: Functions, binding partners and implications .. [82]
55. Loss of Pinch Proteins Causes Severe Degenerative Disc Disease-Lik.. [82]
56. The bone-liver interaction modulates immune and hematopoietic func.. [81]
57. Osteocytes regulate neutrophil development through IL-19: a potent.. [80]
58. Osteocyte TSC1 promotes sclerostin secretion to restrain osteogene.. [79]
59. Prolyl hydroxylase domain proteins regulate bone mass through thei.. [77]
60. Tumour necrosis factor superfamily member 15 (Tnfsf15) facilitates.. [71]
61. 线粒体功能障碍在椎间盘退变中的作用 [71]
62. Loss of phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (Pi.. [68]
63. Pip5k1c Loss in Chondrocytes Causes Spontaneous Osteoarthritic Les.. [67]
64. Kindlin signaling and bone [65]
65. Vangl2 limits chaperone-mediated autophagy to balance osteogenic d.. [60]
66. 粘着斑相关蛋白Kindlin-1在血管内皮细胞的表达及功能研究 [60]
67. Force-induced bone formation is regulated by Kindlin-2 mediated Sc.. [58]
68. Foxo4-and Stat3-dependent IL-10 production by progranulin in regul.. [57]
69. PKC delta null mutations in a mouse model of osteoarthritis alter .. [57]
70. Excess dietary zinc drives a Cushing's-like syndrome in ovariectom.. [57]
71. Editorial: Tissue Stem Cells During Trauma: From Basic Biology to .. [56]
72. Kindlin-2 loss in hepatocytes causes liver dysfunction by stimulat.. [56]
73. Bone marrow adipoq(+) cell population controls bone mass via scler.. [55]
74. Piezo1 activation accelerates osteoarthritis progression and the t.. [54]
75. 几种椎间盘退变动物模型的建立和应用 [53]
76. Deletion of Axin1 in aggrecan-expressing cells leads to growth pla.. [52]
77. Brief research report: Effects of Pinch deficiency on cartilage ho.. [50]
78. Deletion of Axin1 in condylar chondrocytes leads to osteoarthritis.. [46]
79. Development of an Experimental Animal Model for Lower Back Pain by.. [45]
80. TREM2 acts as a receptor for IL-34 to suppress acute myeloid leuke.. [42]
81. PiRNA-63049 inhibits bone formation through Wnt/β-catenin signali.. [39]
82. Specific deletion of Axin1 leads to activation of beta-catenin/BMP.. [39]
83. Sensory nerves directly promote osteoclastogenesis by secreting pe.. [37]
84. miR-204 ameliorates osteoarthritis pain by inhibiting SP1-LRP1 sig.. [36]
85. 2023 January issue Journal of Orthopaedic Translation [32]
86. Regulated cell death in musculoskeletal formation, homeostasis, an.. [32]
87. Advances in osteoarthritis research in 2021 and beyond [31]
88. AMPK activator decelerates osteoarthritis development by inhibitio.. [31]
89. Current progress and trends in musculoskeletal research: Highlight.. [30]
90. Immortalization of mouse primary astrocytes [30]
91. Multiple cullin-associated E3 ligases regulate cyclin D1 protein s.. [30]
92. Comparison of Kindlin-2 deficiency-stimulated osteoarthritis-like .. [29]
93. Primary astrocytes purification and immortalization [29]
94. 椎间盘退变动物模型的研究现状与进展 [24]
95. Single-cell transcriptomic analysis of chondrocytes in cartilage a.. [24]
96. Osteocyte β3 integrin promotes bone mass accrual and force-induce.. [23]
97. Gut microbial metabolite targets HDAC3-FOXK1-interferon axis in fi.. [23]
98. Upregulation of β-catenin signaling represents a single common pa.. [22]
99. An integrated multi-omics analysis reveals osteokines involved in .. [22]
100. Loss of Axin1 in limb mesenchymal cells leads to multiple synostos.. [19]
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