| 题名 | NIR-II fluorescence confocal imaging based on indirect wavefront shaping 基于间接波前整形的近红外二区荧光共聚焦成像研究 |
| 作者 | |
| 发表日期 | 2024
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| DOI | |
| 发表期刊 | |
| ISSN | 2097-1842
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| 卷号 | 17期号:1页码:150-159 |
| 摘要 | Optical aberrations caused by the scattering of biological tissues limit the imaging performance of optical systems. A near-infrared II fluorescence confocal imaging technique based on indirect wavefront shaping was investigated. First, we synthesized a highly efficient near-infrared II range fluorescent probe, where reducing the scattering of biological tissue can realize biopsy imaging with high-contrast. Second, we investigated the adaptive optical method based on indirect wavefront measurement. The indirect wavefront shaping technology was applied to the laser scanning confocal system, enabling the measurement and compensation of optical aberrations caused by biological tissues, and obtaining imaging of biological tissues with a high signal-to-noise ratio. Finally, near-infrared II fluorescence confocal imaging system based on indirect wavefront shaping was deployed and relevant experiments were conducted. The experimental results indicate that the system effectively compensates for the aberrations induced by air plates, scattering media and mouse skull, and increases the final signal intensity by 1.47, 1.95 and 2.85 times, respectively. As a result, the final imaging quality is significantly enhanced. |
| 关键词 | |
| 相关链接 | [Scopus记录] |
| 语种 | 中文
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| 学校署名 | 其他
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| Scopus记录号 | 2-s2.0-85184752437
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| 来源库 | Scopus
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| 引用统计 | |
| 成果类型 | 期刊论文 |
| 条目标识符 | http://kc.sustech.edu.cn/handle/2SGJ60CL/701628 |
| 专题 | 工学院_生物医学工程系 |
| 作者单位 | 1.Engineering Research Center of Photonic Design Software Ministry of Education,College of Science,Minzu University of China,Beijing,100081,China 2.Department of Biomedical Engineering,Southern University of Science and Technology,Shenzhen,518055,China |
| 第一作者单位 | 生物医学工程系 |
| 推荐引用方式 GB/T 7714 |
Tan，Tian,Shi，Tian Yue,Wu，Chang Feng,等. NIR-II fluorescence confocal imaging based on indirect wavefront shaping 基于间接波前整形的近红外二区荧光共聚焦成像研究[J]. Chinese Optics,2024,17(1):150-159.
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| APA |
Tan，Tian,Shi，Tian Yue,Wu，Chang Feng,&Peng，Hong Shang.(2024).NIR-II fluorescence confocal imaging based on indirect wavefront shaping 基于间接波前整形的近红外二区荧光共聚焦成像研究.Chinese Optics,17(1),150-159.
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| MLA |
Tan，Tian,et al."NIR-II fluorescence confocal imaging based on indirect wavefront shaping 基于间接波前整形的近红外二区荧光共聚焦成像研究".Chinese Optics 17.1(2024):150-159.
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| 条目包含的文件 | 条目无相关文件。 | |||||
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