| 题名 | Organocatalytic Enantioselective Construction of Axially Chiral Tetrasubstituted Allenes via 1,6-Addition of Alkynyl Indole Imine Methides with 2-Substituted Indoles |
| 作者 | |
| 通讯作者 | Li, Pengfei; Li, Wenjun |
| 发表日期 | 2022
|
| DOI | |
| 发表期刊 | |
| ISSN | 2193-5807
|
| EISSN | 2193-5815
|
| 卷号 | 11页码:e2021007254 |
| 摘要 | An organocatalytic construction of axially chiral tetrasubstituted allenes featuring indole skeletons has been established. With the aid of chiral phosphoric acid, alkynyl indole imine methides were formed in situ from alpha-(3-indolyl) propargylic alcohols, followed by the asymmetric 1,6-conjugate addition with 2-substituted indoles, furnishing axially chiral indole-containing tetrasubstituted allenes in generally high yields and enantioselectivities. |
| 关键词 | |
| 相关链接 | [来源记录] |
| 收录类别 | |
| 语种 | 英语
|
| 学校署名 | 通讯
|
| 资助项目 | Special Funds of the Taishan Scholar Program of Shandong Province[tsqn201812047]
; Shenzhen Innovation of Science and Technology Commission[20200925151614002]
; Guangdong Provincial Key Laboratory of Catalysis[2020B121201002]
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| WOS研究方向 | Chemistry
|
| WOS类目 | Chemistry, Organic
|
| WOS记录号 | WOS:000730730000001
|
| 出版者 | |
| 来源库 | Web of Science
|
| 引用统计 |
被引频次[WOS]：14
|
| 成果类型 | 期刊论文 |
| 条目标识符 | http://kc.sustech.edu.cn/handle/2SGJ60CL/259276 |
| 专题 | 深圳格拉布斯研究院 理学院_化学系 |
| 作者单位 | 1.Qingdao Univ, Dept Med Chem, Sch Pharm, Qingdao 266021, Shandong, Peoples R China 2.Southern Univ Sci & Technol, Coll Sci, Shenzhen Grubbs Inst, Shenzhen 518055, Peoples R China 3.Southern Univ Sci & Technol, Coll Sci, Dept Chem, Guangdong Prov Key Lab Catalysis, Shenzhen 518055, Peoples R China |
| 通讯作者单位 | 深圳格拉布斯研究院; 化学系 |
| 推荐引用方式 GB/T 7714 |
Wu, Yu,Yue, Zhibin,Qian, Chenxiao,et al. Organocatalytic Enantioselective Construction of Axially Chiral Tetrasubstituted Allenes via 1,6-Addition of Alkynyl Indole Imine Methides with 2-Substituted Indoles[J]. Asian Journal of Organic Chemistry,2022,11:e2021007254.
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| APA |
Wu, Yu.,Yue, Zhibin.,Qian, Chenxiao.,Chen, Xuling.,Li, Fushuai.,...&Li, Wenjun.(2022).Organocatalytic Enantioselective Construction of Axially Chiral Tetrasubstituted Allenes via 1,6-Addition of Alkynyl Indole Imine Methides with 2-Substituted Indoles.Asian Journal of Organic Chemistry,11,e2021007254.
|
| MLA |
Wu, Yu,et al."Organocatalytic Enantioselective Construction of Axially Chiral Tetrasubstituted Allenes via 1,6-Addition of Alkynyl Indole Imine Methides with 2-Substituted Indoles".Asian Journal of Organic Chemistry 11(2022):e2021007254.
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| 条目包含的文件 | 条目无相关文件。 | |||||
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